Clues to restoring normal function in gene that causes cystic fibrosis
A recent study publish in Cell has shown that to restore normal function to the mutant gene product that causes Cystic Fibrosis (CF), it is necessary to correct two structural defects. CF is caused by...
View ArticleGene known to protect against cancer can also promote tumor growth
Researchers at the Spanish National Cancer Research Centre have discovered a gene that can simultaneously protect against cancer and favor its growth. The team wished to ascertain whether the...
View ArticleBone marrow transplant stops symptoms of Rett syndrome in mouse model
Researchers from the Rett Syndrome Research Trust and the Rett Syndrome Research Trust UK have found that a bone marrow transplant can arrest some of the symptoms of the most physically disabling...
View ArticleGenetic variant responsible for resistance to cancer drugs in some patients...
A research team led by scientists at Duke-NUS Graduate Medical School in Singapore have identified a genetic variation that causes some patients to not respond to successful cancer drugs. Tyrosine...
View ArticleResearch team uses stem cells to study gene function in neurological disorders
A research team from Kansas State University, led by professor Mark Weiss, has perfected a technique that uses stem cells to study targeted genetic modifications. Their research aims to advance the...
View ArticleNew gene therapy could treat red blood cell disorders
A team of researchers has designed a gene therapy strategy that could treat the red blood cell disorders beta-thalassemia disease and sickle cell anemia. They also developed a test that can be used to...
View ArticleNew layer of genetic information discovered
A hidden and never before recognized layer of information in the genetic code has been uncovered by a team of scientists at the University of California, San Francisco (UCSF) thanks to a technique...
View ArticleStudy details how human embryonic stem cells regulate development
Yale researchers described how three genes within human embryonic stem cells regulate development in the April 6 issue of Cell Stem Cell. Embryonic stem cells form soon after conception and can become...
View ArticleGenes that can alter growth of stomach cancer cells identified
Scientists from the Duke-NUS and National Cancer Centre in Singapore identified hundreds of novel genes that are mutated in stomach cancer. Dr. Steven G. Rozen and his team used a state-of-the-art DNA...
View ArticleScientists discover that genes switches do more than turn on and off
Scientists have known for decades that genes are turned ‘on’ and ‘off’ by proteins known as transcription factors. They were thought to be like a switch -- either bound to DNA or not. Now scientists...
View ArticleBoston University researchers identify key regulator of inflammatory response
Researchers at Boston University School of Medicine have identified a gene that plays a key role in regulating inflammatory response and homeostasis. This could help lead to the development of...
View ArticleChanges in gene expression of key enzyme could explain high blood pressure in...
A research team from Virginia Commonwealth University School of Medicine has found that changes in the expression of a key inflammatory enzyme called thromboxane synthase are increased in the blood...
View ArticleStudy of half siblings provides genetic clues to autism
New research from Washington University School of Medicine in St. Louis shows that the genetic reach of the disorder often extends to half siblings as well. On the surface, the finding may not be...
View ArticleGenetic abnormalities identified as possible cause of autism
A new study conducted by 15 institutions in three countries reveal that certain genetic abnormalities could lead to autism and other neurodevelopmental disorders. Balanced chromosomal abnormalities...
View ArticleScientists link gene to Asian MRSA epidemic
Scientists from the National Institutes of Health, together with colleagues in China, have identified the Staphylococcus aureus gene (sasX) as playing a pivotal role in establishing...
View ArticleNew technique to improve epigenetics research
Scientists at Cambridge University and the Babraham Institute have demonstrated a new technique that could improve epigenetics research and help scientists better understand how cells develop and...
View ArticleResearchers identify gene mutation responsible for devastating neurological...
Researchers at University of California, Los Angeles have worked with a California family stricken by an extremely rare, devastating disorder that attacks the brain and spine to pinpoint the cause of...
View ArticleResearchers discover first gene linked to missing spleen in newborns
Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen. As a result, those...
View ArticleRestoring hearing with gene therapy
A new study shows that gene therapy could be the key to treating age- and trauma-related hearing loss. Emory University researchers have shown that introducing a gene called Atoh1 into the cochleae of...
View ArticlePrototype test predicts risk of schizophrenia
A study led by Indiana University (IU) has identified and prioritized a group of genes that could indicate the level of risk of developing schizophrenia, the brain disease which affects development...
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